Sagar Vinod Thakre, Chetan S Darne, Monika Parasaram Maske, Dr. Jagdish R Baheti, Dr. Amit Nanasaheb Ingle and Swati Bodhankar

Euphorbia hirta Linn. belongs to the family Euphorbiaceae and is widely known for its medicinal properties and extensively used globally. E. hirta leaves have been investigated for qualitative & quantitative evaluation such as microscopical, physical, and qualitative as well as quantitative evaluation of essential phytoconstituents inclusive of overall phenolic content, flavonoid content & antioxidant potential. This study aimed to screen the antioxidant potential of Hydro alcoholic, Ethyl acetate, and Acetone extracts of E. hirta Linn. Extracts (EH-HA, EH-EA, and EH-AC respectively). The results of 2, 2-diphenyl-1-pycrylhydrazyl (DPPH) radical scavenging assay and lipid per oxidation inhibition assay confirmed that EH-EA turned into the strongest antioxidant (IC50 = 95.05 ± zero.01µg/ml) compared to EH-HA (IC50 = 261.83 ± 0.01 µg/ml) & EH-AC (IC50 = 318.40 ± zero.01µg/mL) extracts. Our study results endorse that E. hirta Linn. extracts possess tremendous antioxidant activity. Results show that this plant might be an awesome supply of natural antioxidants and a probable pharmaceutical complement. The various 3 analyzed extracts; EH-EA extract has the strongest activities and must be used to decide the phytochemicals and mechanisms of these activities.

DOI: 10.22271/phyto.2024.v13.i4a.14993

Pages: 33-43  |  10 Views  4 Downloads