Manas Gupta and Dr. Satya Prakash Singh

Nanoparticle-based systems have emerged as promising tools for multimodal imaging and theranostic applications in cancer detection and therapy. These nanoparticles integrate imaging agents and therapeutic payloads, enabling simultaneous imaging and phototherapy, such as photodynamic therapy (PDT) and photothermal therapy (PTT). Various nanoparticle platforms, including inorganic (gold, upconversion, carbon nanotubes), organic (polymeric, liposomes, micelles), and hybrid systems, have been developed for combined imaging modalities (optical, MRI, CT, PET) and phototherapy. The review explores imaging-guided phototherapy strategies, theranostic applications, and challenges like biocompatibility, light penetration, and clinical translation. It also discusses emerging trends like stimuli-responsive nanoparticles and artificial intelligence integration, highlighting the potential of these nanoparticle-based platforms to revolutionize cancer diagnosis and treatment through improved imaging, targeted therapy delivery, and real-time monitoring.

DOI: 10.22271/phyto.2024.v13.i3c.14963

Pages: 236-243  |  200 Views  94 Downloads