Dr. Umakant N Rabb

The drugs which act on nervous system are termed as nootropic drugs which help in boosting the cognitive and intellectual ability. The Ayurvedic medicinal plants which help for improving cognitive function owing to their no adverse effects and provides a list of herbs known for nootropic activity as well as their multi-dimensional utility in various conditions. The classification of medicinal plants, as per the dominant pharmacological or therapeutic activity on mental functions have been enlisted. Viz; the CNS active medicinal plants, which have emerged are Rauwolfia serpentina are Mucuna pruriens for Parkinson’s disease, Withania somnifera, as anxiolytic, Centella asiatica and Bacopa monniera for learning and memory disorders, Acorus calamus as anxiolytic and, Ocimum sanctum as an antistress agent etc drugs. The interface of molecular psychiatry and the active principles of some of these plants will be a major field for new developments in neuro-pharmacology. The neuro-pharmacology drugs affects the function in the nervous system and the neural mechanisms through which they influence the behaviour of the person. The neuro-pharmacology has two branches viz; behavioural neuropharmacology and molecular neuropharmacology. The behavioral neuro-pharmacology deals with the study of drugs affects human behavour including study of the drug dependence and addiction i.e action on human brain. Whereas the molecular neuropharmacology is the study of neurons and the neurochemical pathway and the interactions. Since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, co-transporters, ion channels and receptor protiens in the central and peripheral nervous systems. Studying these interactions the researchers developed drugs to treat many different neuro neurological disorders including pain, nero-degenerative diseases such as Parkinson’s diseases, Alzheimer’s diseases, psychological disorders, addiction and many others. The Present article is a review to update knowledge on selected Ayurvedic medicinal plants their pharmacological properties, major chemical constituents, therapeutic actions, pre clinical studies, safety and possible mode of action of the selected herbs from Ayurvedic pharmacopoeia.
Aims and Objectives: The aim of the present work is to highlighted the concept of medicinal herbs and their impact on nervous system through different animal experiments.
The objective is to elaborate the concept of medicinal herbs acting on human nervous system based on the different Ayurvedic texts along with research updates with the help of modern digital data.
Material and Methods: The concepts, assessment and literary survey was done on the basis of Ayurvedic texts books and digital data.
 

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