Journal of Pharmacognosy and Phytochemistry
Vol. 9, Issue 3 (2020)
Grinding: A novel method for synthesis of potential antifungal pyrazoles
Author(s):
Suprita, Pardeep Loura, Suman, Susheel Gulati and Rajvir Singh
Abstract:
A benign, rapid and solvent free synthesis of pyrazoles have been done by grinding techniques by using substituted benzaldehyde, malanonitrile and 2,4-dinitrophenyl hydrazine and comparison has been done with conventional method in which solvent is used. Special features of grinding techniques involve ecofriendly, non hazardous, excellent yield and short time reaction. The synthesized compounds have been screened for their antifungal activity against
Asperillus niger and
Rhizoctonia solani. These synthesized compounds were characterized by IR,
1HNMR and melting point.
Pages: 1585-1589 | 683 Views 252 Downloads
Suprita, Pardeep Loura, Suman, Susheel Gulati and Rajvir Singh. Grinding: A novel method for synthesis of potential antifungal pyrazoles. J Pharmacogn Phytochem 2020;9(3):1585-1589.