Author(s):

N Bharathi, R Caroline Nirmala, B Vinothini and N Kumaravadivel

Abstract: Mango fruit (Mangifera indica) is one of the important economic fruit crops because of its good smell, delicious taste, excellent flavor, and attractive fragrance. It also called as king of fruits. However, one of the constraints of markets is disease, especially anthracnose disease caused by fungus Colletotrichum gloeosporioides. It causes yield loss of about 10-50%. In silico analysis was done to identify the competence of the fungicides. Beta tubulin of the fungus was found to be important protein involved in causing the disease. The three dimensional structure of Beta tubulin was modeled through Homology modeling with 2XRP_A as template. The protein-Ligand interaction studies has been carried out to analyse the competence of fungicides. Docking studies reveals that ligands such as Benomyl and Azoxystrobin has good binding affinity with the receptor and express its competency towards controlling anthracnose disease.

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