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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 4 (2019)

Determination of bioactive components of Pronus avium L Leaf

Author(s):

Ahamefula A Ahuchaogu and Chitua E Igara

Abstract:
Medicinal plants are a source of naturally active compounds used extensively in herbal medicine worldwide for treatment of many ailments, promote human health and longevity in many regions of the world since ancient times. Plant-derived bioactive compounds in the past few decades have become of great interest owing to their rich ethnomedicinal and nutraceutical potentials and versatile pharmaceutical applications The objective of the study was to determine the content of bioactive compounds using Gas Chromatography-Mass Spectrometry technique. GC-MS analysis confirmed the occurrence of a total 24 phytocompounds. These compounds belong to different chemical classes and most of them are reported to exhibit important biological activities. Some of the major compounds included, 2-Methyl-2-[(1-E,3Z-E,5E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexenyl)-1,3,5-hexatrienyl]-1,3-dioxolane (29.09%), Cyclopentaneundecanoic acid, methyl ester (15.5%), 2-Furanmethanol, tetrahydro-α,α,5-trimethyl-5-(4-methyl-3-cyclohexen-1-yl)-, [2S-[2α,5β(R*)]]-(2-Furanmethanol, tetrahydro-α,α,5-trimethyl-5-(4-methyl-3-cyclohexen-1-yl)-, [2S-[2α,5β(R*)] (9.855%), The biological activity of these phytochemicals includes, Anticancer, Anti-inflammatory, Antiprotozoal, Anti-myelomic, Antileishmanial, Antioxidant and Antimigrain.

Pages: 2668-2679  |  1058 Views  507 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Ahamefula A Ahuchaogu and Chitua E Igara. Determination of bioactive components of Pronus avium L Leaf. J Pharmacogn Phytochem 2019;8(4):2668-2679.

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