Author(s):

Anugraha S, Vennila L, Asaikumar L, Vijayakumar N, Panbilnathan A, Ajay Krishnan U and Arya R

Abstract: Natural antioxidants have an important role in the prevention of many diseases and promotion of health. Among natural antioxidants, flavonoids and other phenolic compounds are powerful antioxidants. The antioxidant activities of the methanol extracts from the leaf and root extracts of Elephantopus scaber (E. scaber) were assessed by using 1,1-diphenyl-2-picryl hydroxyl (DPPH) quenching assay, 2,2’-azinobis-3-ethylbenzothiozoline-6-sulfonic acid (ABTS) decolorization test, reducing power activity and ferric reducing antioxidant power (FRAP) and superoxide anion, hydrogen peroxide (H₂O₂) radical, hydroxy radical scavenging assay. In the present study, reducing power, FRAP and the free radical scavenging activity were increased in a dose depending manner. The antioxidant activity of the samples was comparable with that of the standard antioxidant butylated hydroxyl toluene (BHT). The results indicate that both the leaf and root extracts of E. scaber displayed antioxidant activity, which may be attributed to the presence of adequate phenolic and flavonoid compounds. This study suggests that E. scaber extracts exhibit great potential for antioxidant activity and may be useful for the nutritional and medicinal purpose.

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