Author(s):

Ankita Raisagar, Dr. Chanchal Deep Kaur, Hemant A Sawarkar, Lokesh Kumar, Anita Raisagar, Arjun Karmakar and Mahendra Sahu

Abstract: The aim of the study was the comparative study of the wound healing potential of the bark of Ficus religiosa and Ficus benghalensis. The locally available plants like Ficus religiosa and Ficus bengalensis have the capability to cure diseases traditionally since long years, due to this reasons these two plants were selected for the study. It was found that ethanol and hydroalcoholic extraction of two plants that is Ficus religiosa and Ficus benghalensis showed high wound healing activity. The plant extracts were used to study their phytochemical compositions i.e. total phenols contents, flavonoids contents, terpenoids content and proteins contents. Most of the biologically active phytochemical presents in the ethanol extract. The results obtained that Wound healing potential of the bark of Ficus religiosa is higher than the bark of Ficus benghalensis. The antimicrobial activity was evaluated by well diffusion method while wound healing effect in rats was evaluated using the in vitro and in vivo wound model infected. In case of antimicrobial activity the ethanolic extract of Ficus religiosa showed better antimicrobial activity. The ethanolic and hydroalcoholic extract of bark of two plant that is Ficus religiosa and Ficus benghalensis compared for in vitro wound healing activity. For in vitro Wound healing activities including Inhibition of RBC haemolysis was performed. In Inhibition of RBC haemolysis, when the decrease in absorbance at 517nm it increases the RBC membrane stabilization activity of the plants sample. For RBC membrane stabilization experiment Soframycin taken as the standard solution and for in vitro wound healing activity using excision wound model was performed. In both case in vivo and in vitro wound healing model ethanolic extract of Ficus religiosa having higher wound healing activity as compared to hydroalcoholic extract.

Pages: 1815-1821  |  1708 Views  940 Downloads

Download (803KB)