Journal of Pharmacognosy and Phytochemistry
Vol. 8, Issue 1 (2019)
Molecular docking of embelin against human mono amine oxidase- a (MAO-A) enzyme
Author(s):
Nanthini B, Selvakumari E, Gopal V and Ranganadhan S
Abstract:
Vitiligo is a dermatological disorder. Free radical and reactive oxygen species are well known key factor for the pathogenesis of vitilgo. The present paper reports the formulation of poly herbal capsule, Molecular docking of embelin, a major constitution from the poly herbal capsule with the receptor mono amino oxidase-A enzyme and the
in-vitro antioxidant activity of the poly herbal capsule by DPPH radical scavenging and total antioxidant assay method. The result showed the inhibitory effect of embelin against the receptor MAO-A. The
in-vitro antioxidant activity of the formulated poly herbal capsule showed remarkable effect similar to the standard drug Ascorbic acid. The result obtained validates the traditional uses of the formulated poly herbal capsule in the treatment of vitiligo in siddha system of medicine.
Pages: 1642-1646 | 927 Views 279 Downloads
Nanthini B, Selvakumari E, Gopal V and Ranganadhan S. Molecular docking of embelin against human mono amine oxidase- a (MAO-A) enzyme. J Pharmacogn Phytochem 2019;8(1):1642-1646.