Author(s):

A Antony Lawrence and Dr. J. Thomas Joseph Prakash

Abstract: The present study aimed to synthesize metal nanoparticles using plant and metal. This natural method was proceeded by silver nitrate mixed with Manilkara hexandra leaf extract to form silver nanoparticles. The Manilkara hexandra leaf extract contains phytocompounds which were analyzed by phytochemical screening and gas chromatography-mass spectrometry analysis and fifteen compounds were identified in the aqueous leaf extract. These phytocompounds act as reducing and capping substance to form silver nanoparticles; it is a bottom-up approach technique. Silver nanoparticles are identified by the change of color and characterized by using various techniques. UV-visible spectrum ranging from 441 nm to 446 nm reveals silver nanoparticles. The Fourier transform infrared spectroscopy comprises biomolecules capping silver nanoparticles. The field emission scanning electron microscopy shows the range of 37 nm to 92 nm sizes and Energy-dispersive X-ray spectroscopy shows elements such as Ag, Cl, O, Si. The X-ray powder diffraction spectra correspond to lattice planes (111), (200), (220) and (311). Particle size analyzer shows the 29nm and 181nm range. The negative value (-13 nm) shows the high stability of the compound in Zeta potential. Silver nanoparticles is also indulged in thermal analysis like Thermogravimetry/Differential Thermal Analysis and Differential scanning calorimetry. TGA show that 46.56% of weight loss. DSC describe that the materials are stable until 278ËšC. The Silver nanoparticles are effective in antioxidant (DPPH method) and antimicrobial assays. This depicts clearly that the nanoparticles can be applied in drug delivery system.

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