• Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 7, Issue 6 (2018)

Synthesis, characterization and Antifungal activity of transition metal (II) complexes of Schiff base derived from p-amino acetanilide and salicylaldehyde

Author(s):

Dr. Meenakshi Munjal

Abstract:
Tridentate Schiff base (L) has been synthesized by condensation of salicylaldehyde and p-amino acetanilide in ethanol and treating with copper, nickel, cobalt and zinc chlorides form metal complexes. The synthesized compounds are characterized by analytical and spectral methods. The results indicate that the complexes are having ML2 the composition. Moreover, geometry of the complexes is confirmed from electronic absorption and magnetic susceptibility data. The data show that all the complexes are distorted octahedral geometry around the central metal ion. The synthesized complexes were also exposed to various fungi to establish their bioactivities which show significant results. All the synthesized compounds are active against fungi but metal complexes are more active than ligand. Minimum Inhibitory Concentrations (MIC) values of synthesized compound range 25-55 g/ml against fungal species.

Pages: 864-866  |  1209 Views  386 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Dr. Meenakshi Munjal. Synthesis, characterization and Antifungal activity of transition metal (II) complexes of Schiff base derived from p-amino acetanilide and salicylaldehyde. J Pharmacogn Phytochem 2018;7(6):864-866.

Call for book chapter