Author(s):

B Lokesh, R Deepa and K Divya

Abstract: Coleus forskohlii is an important medicinal plant native to India. It has been used in traditional Ayurvedic medicine for curing various disorders and this is the only source of diterpenoid forskolin. A tuberous roots are found to be a rich source of forskohlin (coleonol) used as a potential drug for hypertension, congestive heart failure, eczema, colic, respiratory disorders, painful urination, insomnia and convulsions. Clinical studies of the plant further support these traditional uses, indicating therapeutic benefits in asthma, angina, psoriasis and prevention of cancer metastases, where decreased intracellular cAMP level is believed to be a major factor in the development of the disease process. This article gives a comprehensive look on Coleus as a natural product and aims to present it in a brief manner for the researchers, scientist, botanists, pharmacognosists and herbalists to refresh their knowledge about coleus. This paper also comprehensive account of the plant classification, Phytochemistry, mechanism of action, medicinal and other uses, cytogenetic, botanical distribution, crop improvements and varieties, biotechnological approaches, complete cultivation aspects and postharvest technology for higher forskohlin production reports are included in view of the many recent findings.

Pages: 2856-2864  |  3692 Views  2246 Downloads

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