Author(s):

Surjyo Jyoti Biswas, Santosh Kumar Giri, Nimai Chandra Saha, Paramita Banerjee, Subrata Raha and Akhil Pandey

Abstract: Bixa orellana L. is a plant widely grown in tropics which has gained attention due to its pharmacological properties. Further it is a dye yielding plant which is obtained from the seeds which contains bixin and norbixin. Phytochemical evaluation, acute toxicity studies and antimicrobial efficacy of seed extract was conducted by deploying wide variety of protocols. Investigation revealed presence of variety of phytoconstituents such as alkaloids, flavonoids etc. Further GC MS studied showed the presence of 23 compounds some of which are phyto-estrogenic and have antioxidant properties. Antibacterial studied showed there was a clear zone of inhibition and extract was effective against both gram-positive and gram-negative bacteria when compared to broad spectrum antibiotic streptomycin. Further, the extract did not reveal any genotoxic potential at higher doses of treatment. Bixa orellana may be considered an important plant which has future prospects to be used against various ailments.

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