Author(s):

Amit Kumar Deb, Md. Abdul Motaleb Bhuiya and Mohammad Tohidul Amin

Abstract: Thrombus formed in blood vessel results in thrombo-occlusive disease such as myocardial infarction or cerebral infarction. The aim of the study is to determine the thrombolytic potentiality of ethanolic extracts of Amaranthus spinosus (Katamarish). In that study streptokinase used as a positive control and water used as a negative control. By using an in vitro thrombolytic model Amaranthus spinosus (Katamarish) showed 41.87% thrombolytic activity. Besides Streptokinase showed 86.20% thrombolytic and distilled water showed 5.20% clotlysis activity. From our study it was found that Amaranthus spinosus possesses thrombolytic properties that could lyses blood clots when subjected to in vitro study. But In vivo clotlysis activities and active components for clotlysis properties need to be discovered further. Our present in vitro studies proposed that further studies need to be carried out for using Katamarish as thrombolytic agent to the treatment of the patient suffering from thrombo-occlusive diseases.

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