Author(s):

Kiran B Kotade and Shivanand N Hiremath

Abstract: Standardization the process of developing and implementing technical standards and to maximize compatibility, safety, repeatability and quality of the drugs is one of the important measures in view of the various practical problems encountered from time to time especially in the field of herbal drugs and Ayurveda. Scientific data pertaining to the standardization of the herbal drugs could be of immense value to substantiate efficacy, safety or toxicity of an herb. Hence present study was intended to standardize Gymnosporia montana fruit extracts, as it is an important plant which possess medicinal actions like its use in the treatment of dysentery, jaundice, toothache, vermifuge etc. Standardization of fruit of Gymnosporia montana were carried out using phytochemical qualitative analysis and quantitative flavonoid analysis to assess the quality and purity of drug. The different extracts of Gymnosporia montana fruit were prepared starting with a highly nonpolar solvents viz., Petroleum ether followed by Chloroform, and Ethanol (95%) using Soxhlet apparatus. The present study assessed qualitative phytochemical characteristics of different extracts which revealed presence of alkaloids, flavonoids, glycosides, phenols, anthraquinones, carbohydrates, saponins, phytosterols and triterpenoids. It indicates G. montana was a good source of flavonoids. Total flavonoid contents were calculated as quercetin equivalent from calibration curve prepared using quercetin and was found to be 12.15 mg quercetin equivalents/g respectively. Results indicated the authenticity of the herbal drugs used in the study. Study was successful in establishing quality standards for the fruit of Gymnosporia montana.

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