Author(s):

Sachin B Somwanshi, Shivanand N Hiremath and Rakesh K Jat

Abstract: Standardization the process of developing and implementing technical standards and to maximize compatibility, safety, repeatability and quality of the drugs is one of the important measures in view of the various practical problems encountered from time to time especially in the field of herbal drugs and Ayurveda. Scientific data pertaining to the standardization of the herbal drugs could be of immense value to substantiate efficacy, safety or toxicity of an herb. Hence present study was intended to standardize Sesamum indicum L seed extracts, since Sesamum indicum L. (sesame or til) is an important food, oil, medicinal and religious crop in India. Standardization of seeds of Sesamum indicum L. were carried out using organoleptic characterization and chemical characterization as moisture content & ash value to assess the quality and purity of drug. The oil was extracted from seed of Sesamum indicum L. by solvent extraction method using Soxhlet apparatus with suitable solvents as Petroleum ether (40- 60°C), ethanol, benzene and n-hexane. The percentage oil yield on weight of the dried seeds was 46% in the ethanol extract and was found to most suitable as the yield is more and is less toxic and economic. The present study assessed phytochemical characteristics of the oil extracted from seeds of Sesamum indicum L. Qualitative phytochemical analysis of extracts revealed presence of alkaloids, flavonoids, glycosides, phenols, anthraquinones, tannins, carbohydrates and proteins extracts. The oil quality parameters were accessed in terms of acid value, free fatty acid value, saponification value, iodine number and peroxide value. Results indicated the authenticity of the herbal drugs used in the study. Study was successful in establishing quality standards for the seeds of Sesamum indicum L. These preliminary studies may offer great help in initial procurement and assessment of quality of the crude drugs when these are being used as raw materials for preparations of herbal formulations.

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