Author(s):

Tharini P, Sivaraj C, Arumugam P and Manimaran A

Abstract: Ficus benghalensis belongs to the family Moraceae is a giant evergreen tree with spreading branches which are supported by aerial roots that go down into the soil to form the 'props'. The milky latex is applied externally for treating pains in rheumatism and in lumbago. The infusion of the bark is used against dysentery, diarrhoea and diabetes. The study aims to evaluate its antioxidant activities and GC-MS analysis of ethanol fruit extract of F. Benghalensis. The antioxidant assays such as DPPHË™ radical, ABTS^Ë™+ radical cation, OHË™ radical and NOË™ radical scavenging assays, phoshomolybdenum reduction and Fe³⁺ reducing power assays were carried out for fruit extract. The maximum DPPHË™ radical scavenging activity was 75.74±5.30% at 60 µg/mL concentration and the IC₅₀ was 32.20 μg/mL concentration. The maximum NOË™ radical scavenging activity was 51.96±3.64% at 60 µg/mL concentration and the IC₅₀ was 57.74 μg/mL concentration. The maximum ABTS^Ë™+ radical cation scavenging activity was 79.57± 5.57% at 30 µg/mL concentration and the IC₅₀ was 13.69 μg/mL concentration. The maximum OHË™ radical scavenging activity was 57.02±3.99 % at 60 µg/mL concentration and the IC₅₀ was 34.37 μg/mL concentration. The maximum phosphomolybdenum reduction was 80.48±5.63 % at 60 µg/mL concentration and the RC₅₀ was 13.78 μg/mL concentration. The maximum Fe³⁺ reduction was 69.19±4.84 % at 60 µg/mL concentration and the RC₅₀ was 18.71 μg/mL concentration. GC-MS analysis showed different ester derivative compounds present in the fruit extract of F. Benghalensis.

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