Abstract:
In the present study the acetone, methanol and aqueous extracts of
Sida acuta Burm
. F
, Sida alnifolia L
., Sida fryxelli Sivarajan
& Pradeep
(I.C
.) and
Sida rhombifolia L
., whole plant were screened for the presence of phytochemical components and tested for antibacterial activity against
Escherichia coli, Staphylococcus aureus and
Klebsiella pneumonia. Result revealed the presence of phenolics, saponins, flavonoids, alkaloids, tannins, steroids, carbohydrates and proteins. The study indicates that phytochemical constituents of the four species of
Sida are different. Acetone extract of
Sida didn’t show significant activity compared to the standard amoxicillin. Aqueous and methanolic extracts showed significant antibacterial property at higher dose. The different species of
Sida studied didn’t show significant antibacterial competence against
E.
coli. Prominent anti-bacterial activity was shown by
Sida acuta against
Staphylococcous aureus (20.5 mm) at 200 µg concentration in methanolic extract. In UV-VIS studies of the extracts in the range of 190nm to 400nm showed large number of peaks indicated the presence of active components in the extract.
Asha A, Shameema Farsana and EC Baiju. Phytochemical profiling and antibacterial activity of selected Sida species against common human pathogenic bacteria: An in vitro study. J Pharmacogn Phytochem 2018;7(3):1201-1205.