Volume 2, Issue 1

 

Antiulcer Activity of an Isolated Compound (SP–1) from the Seeds of Nirmali (Strychnor potatorum Linn.)

 

Author(s): Prasenjit Mitra, Tanaya Ghosh and Prasanta Kumar Mitra*
Professor & Head, Department of Medial Biotechnology,Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India

Abstract: An active compound (SP-1) was isolated from the seeds of  Nirmali (Strychnor potatorum Linn.) and its antiulcer activity was studied against ethanol, hydrochloric acid, indomethacin, stress and pyloric ligation induced  gastric ulceration in albino rats. A significant antiulcer activity of  SP-1was observed in all the models. SP-1 thus provides a scientific rationale for the use as antiulcer drug.

 

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